Winners 2020

Professor David Gardner (Australia)

Are we discarding euploid blastocysts as a result of outdated criteria for assessing fertilization?

“The objective of this research is to determine the frequency and characterize embryo development of abnormally fertilized oocytes, and to test the ploidy and chromosomal constitution of resulting blastocysts, in order to identify viable embryos for clinical use”

– Professor David Gardner

Team members: Dr. Sharyn Stock-Meyer, Dr. Lisa Lee

Professor Antonio La Marca (Italy)

Desogestrel versus GnRH antagonist (ganirelix) in IVF/ICSI patients undergoing Ovarian Stimulation: a randomized controlled trial (RCT) (DEGOStrial)

“The aim of this research will be to investigate the use of Desogestrel in controlling the LH surge during ovarian stimulation in IVF/ICSI cycles with the trial being conducted as a noninferiority trial in which the primary efficacy endpoint will be the number of oocytes retrieved per patient”

– Professor Antonio La Marca

Dr. Tomasz Rokicki (Poland)

Effectiveness of frozen embryo transfer in a natural cycle, based on hormonal monitoring without ultrasound.

“This study is designed to prove the hypothesis that in normally menstruating women with regular cycles there is no need to perform ultrasound to check the cycle, detect the ovulation day and therefore schedule the embryo transfer. This is extremely important for patients who live far away and cannot attend many visit and ultrasound checks but can go to a local lab for hormonal blood tests”

– Dr. Tomasz Rokicki

Professor Roberto Marci (Switzerland)

Microbiota as environmental factor with a role in endometrial receptivity

“The primary objective of this project is the definition of the role of environmental factors as microbial infections in modifying endometrial receptivity, with a secondary objective of the definition of the mechanisms implicated in the modification of endometrial receptivity”

– Professor Roberto Marci

Team members: Professor Roberta Rizza, Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Italy

Professor Bruno Salle (France)

A major progress in the preservation of female fertility: complete in vitro folliculogenesis in human fetal ovarian tissue in a bioreactor, and study of the mature oocytes' quality obtained.

“Our final goal is to product fertile oocytes thanks to the bioreactor. Global issues are obviously carrying high societal impact for human fertility preservation. Such robustness is of considerable interest in the context of fertility preservation. To achieve this final goal, our objectives are to finish this in vitro folliculogenesis and to check the quality of the mature oocytes obtained”

– Professor Bruno Salle

Team members: Dr. Elsa Labrune, Dr. Jacqueline Lornage, Cyrielle Fournier, Pr. Laurent David,
Dr. Alexandra Montembault